Manfred Pharmaceuticals Product List  Manfred Pharmaceuticals Product List

Our Product List

 
  • 1. PEPCEF 200 DT
  • Product - 1

    PEPCEF 200 DT

    Each dispersible uncoated tablet contains
    Cefixime IP as Trihydrate equivalent to anhydrous Cefixime……… 200 mg.
    CLINICAL PHARMACOLOGY & ANTI-MICROBIAL SPECTRUM

    As with other cephalosporins, bactericidal action of cefixime results from inhibition of cell-wall synthesis. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime.

    PHARMACOKINETICS

    Cefixime given orally, is about 40%-50% absorbed from the GI tract. The mean elimination half-life (t1/2) of 3h. Urinary excretion accounts for between 12 and 34% of an orally administered dose. Cefixime is not removed to a significant degree by either peritoneal dialysis or haemodialysis. Cefixime is mainly excreted unchanged in bile and urine.

    INDICATIONS

    * Urinary tract infections * Upper and lower respiratory tract infections * Acute otitis media * Gonococcal urethritis

    DOSAGE AND ADMINISTRATION

    Adults & Children [weighing more than 50 kg or older than 12 yr of age] : 200-400 mg in single or divided doses.

    Children 6 mo to 12 yr of age [or weighing under 50 kg]: 8 mg/kg/day as a once-daily dose or in 2 divided doses of 4 mg/kg every 12 h.

    CONTRAINDICATIONS

    Cefixime is contraindicated in patients with a known hypersensitivity to cephalosporin group of antibiotics.

  • 2. Odynix-SP
  • Product - 2

    Odynix-SP

    Each tablet contains
    Aceclofenac IP………………………… 100 mg
    Paracetamol IP……………………….. 325 mg
    Serratiopeptidase IP ………………. 15 mg
    MECHANISM OF ACTION

    Aceclofenac directly blocks PGE 2 secretion at the site of inflammation by inhibiting IL-Beta & TNF and COX enzyme in the inflammatory cells (Intracellular Action).

    Paracetamol produces analgesia by elevation of the pain threshold and antipyresis through action on the hypothalamic heat-regulating center.

    Serratiopeptidase hydrolyses bradykinin, histamine and serotonin, and reduces dilatation of blood capillaries and controls permeability. Serratiopeptidase blocks plasmin inhibitors thus helping the fibrinolytic activity of plasmin and helps clearance of exudates, reduces swelling and improves microcirculation.

    INDICATIONS

    Odynix -SP Tablets are indicated for relieving inflammation and edema associated with conditions such as musculoskeletal disorders (sprains, strains, tendonitis, bursitis, lumbago), trauma, infection, respiratory-tract congestion etc.

    DOSAGE AND ADMINISTRATION

    Oral: Adults: 1 tablet to be taken 2 times daily, or as prescribed.

    HOW SUPPLIED

    10 Tablets per strip

  • 3. Odynix-P
  • Product - 3

    Odynix-P

    Each tablet contains
    Aceclofenac IP………………………… 100 mg
    Aceclofenac IP………………………… 100 mg
    MECHANISM OF ACTION

    Aceclofenac directly blocks PGE 2 secretion at the site of inflammation by inhibiting IL-Beta & TNF and COX enzyme in the inflammatory cells (Intracellular Action).

    Paracetamol produces analgesia by elevation of the pain threshold and antipyresis through action on the hypothalamic heat-regulating center.

    INDICATIONS

    Odynix - P Tablets are indicated in the management of chronic arthroses such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It is also useful for relieving pain & inflamation associated with acute musculoskeletal disorders.

    DOSAGE AND ADMINISTRATION

    Oral: Adults: 1 tablet to be taken 2 times daily, or as prescribed.

    HOW SUPPLIED

    10 Tablets per strip

  • 4. Ralus-D
  • Product - 4

    Ralus-D

    Each enteric coated Sustain Release Capsules contains
    Rabeprazole sodium IP ………. 20 mg
    Domperidone …………………….. 30 mg
    MECHANISM OF ACTION

    Rabeprazole belongs to a class of antisecretory compounds (substituted benzimidazole proton- pump inhibitors) that do not exhibit anticholinergic or histamine H2 -receptor antagonist properties.

    Rabeprazole block gastric acid secretion by inhibiting gastric H+/K+-adenosine triphosphatase in gastric parietal cells.

    Domperidone is dopamine antagonist that increases gastric emptying, small bowel transit, and the tone of the lower oesophageal sphincter.

    INDICATIONS

    Ralus - D Tablets are indicated for relieving Gastro-oesophageal reflux disease, Hypersecretory conditions, Active peptic ulcer disease, H.pylori infection etc.

    DOSAGE AND ADMINISTRATION
    Gastro-oesophageal reflux disease (oral)

    Adult: For erosive oesophagitis: 20 mg once daily in the morning for 4-8 wk. Maintenance: 10-20 mg once daily according to response. For non-erosive oesophagitis: 10 mg once daily for 4 wk, upon symptom resolution, may continue with 10 mg once daily when necessary or as prescribed.

    Hypersecretory conditions (oral)

    Adult: Initially, 60 mg daily adjusted according to response. Max dose: 120 mg daily or as prescribed.

    Active peptic ulcer disease (oral)

    Adult: 20 mg daily given for 4-8 wk for duodenal ulcer and 6-12 wk for gastric ulcer or as prescribed.

    H.pylori infection

    Adult: As a combination with two antibacterials: 20 mg bid combined with clarithromycin 500 mg bid and either amoxicillin 1 g bid or metronidazole 400 mg bid. To be taken for a week or as prescribed.

    HOW SUPPLIED

    10 Tablets per strip

  • 5. Ralus 20
  • Product - 5

    Ralus 20

    Each enteric coated Sustain Release Capsules contains
    Rabeprazole sodium IP ………. 20 mg
    MECHANISM OF ACTION

    Rabeprazole belongs to a class of antisecretory compounds (substituted benzimidazole proton- pump inhibitors) that do not exhibit anticholinergic or histamine H2 -receptor antagonist properties.

    Rabeprazole block gastric acid secretion by inhibiting gastric H+/K+-adenosine triphosphatase in gastric parietal cells.

    INDICATIONS

    Ralus - 20 Tablets are indicated for relieving Gastro-oesophageal reflux disease, Hypersecretory conditions, Active peptic ulcer disease, H.pylori infection etc.

    DOSAGE AND ADMINISTRATION
    Gastro-oesophageal reflux disease (oral)

    Adult: For erosive oesophagitis: 20 mg once daily in the morning for 4-8 wk. Maintenance: 10-20 mg once daily according to response. For non-erosive oesophagitis: 10 mg once daily for 4 wk, upon symptom resolution, may continue with 10 mg once daily when necessary or as prescribed.

    Hypersecretory conditions (oral)

    Adult: Initially, 60 mg daily adjusted according to response. Max dose: 120 mg daily or as prescribed.

    Active peptic ulcer disease (oral)

    Adult: 20 mg daily given for 4-8 wk for duodenal ulcer and 6-12 wk for gastric ulcer or as prescribed.

    H.pylori infection

    Adult: As a combination with two antibacterials: 20 mg bid combined with clarithromycin 500 mg bid and either amoxicillin 1 g bid or metronidazole 400 mg bid. To be taken for a week or as prescribed.

    HOW SUPPLIED

    10 Tablets per strip

  • 6. RHINOFRED
  • Product - 6

    RHINOFRED

    Each 5 ml suspension contains
    Paracetamol IP ………………………………….. 250mg
    Phenylephrine IP ……………………………….. 5mg
    Chlorpheniramine Maleate IP …………….. 2mg
    MECHANISM OF ACTION

    Rhinofred contains clinically proven analgesic-antipyretic paracetamol with decongestant phenylephrine and antihistaminic chlorpheniramine maleate.

    Paracetamol produce analgesia by elevation of pain threshold and antipyretic effect through action on hypothalamic heat regulating center.

    INDICATIONS

    Rhinofred Suspension is indicated for relieving sinus pain and headache, adjunct with antibacterial in sinusitis, tonsillitis and otitis. Nasal blockage, rhinorrhia and sneezing etc.

    DOSAGE AND ADMINISTRATION

    Oral: 2 to 4 years age: 5 ml to be taken 2 times daily, or as prescribed.

    HOW SUPPLIED

    60 ml pet bottle.